This work establishes the methodological basis to investigate quality evaluation methods in terms of “auditory-cognition research validation” and “auditory-cognition-centric VR evaluation” within the interdisciplinary priority program DFG SPP2236 AUDICTIVE (AUDItory CogniTion in Interactive Virtual Environments). Across the different projects in the program, we identified potential dependent and independent variables influencing auditory cognition in IVEs and potential covariates. Subsequently, a methodology matrix was generated related to independent variables (scene classification, VR-technology, user groups) and dependent variables (cognitive performance, behaviour, physiological measures, subjective evaluation). By collecting the information via the methodology matrix from all projects in the program, we systematically categorize the research paradigms, data collection methods, realization of the virtual environments, and the methods to evaluate quality, as a first step towards developing a comprehensive database, targeting an Open Science approach. Results indicate that (i) the subjective evaluation method is a common variable across projects, that (ii) the available VR- (or AR-, MR-) technology used within the projects is highly diverse and provides a versatile quality evaluation environment from a technological point of view, and that (iii) a vocabulary for scene description has to be established across projects and disciplines, in order to set the basis for a common ground.